Nineteen of the Russian's twenty-one championships have been achieved on hard courts
A resurgent Medvedev claimed his initial trophy for 882 days with victory over Corentin Moutet in the competition title decider.
The Russian, a ex- number one, has endured a torrid year, managing just a single victory at the Grand Slams and suffering a difficult moment at the New York tournament.
His varied form on the professional circuit - and struggles with his serve in particular - led to him dropping out of the world's top 10 and eventually separating with long-time mentor Cervara.
Presently working with his coach and Goetzke, Medvedev has gradually progressed in the past month - peaking in a hard-fought three-set triumph over opponent Moutet.
It is Medvedev's first title after the Italian tournament and initial on a hardcourt since spring of the previous year.
Success also indicates Medvedev has achieved 21 championships at twenty-one distinct tournaments.
"This marks the first occasion I am participating in a tournament with my both daughters together, so to get a championship is especially meaningful," commented world number 14 Daniil Medvedev.
"This title is in dedication of my second daughter Victoria, because the initial championship I achieved when my child Alisa was born was for her."
The tennis star, the former major winner, had lost his past six championship matches, comprising in the German tournament previously this season.
His defensive strategy and frequent outbursts on court had caused some to question if his skill to perform at the top level was over.
However the 29-year-old has implemented adjustments in the past month, making an effort to approach the net and compete aggressively, reinforced by an better serving game.
Medvedev fought back from a break down in the opening set against the difficult Frenchman, winning 4 of the concluding five games to gain the advantage.
The competitors swapped break points in the second set before Moutet, bidding for his first ATP Tour title, seized the initiative to push for a final set.
Moutet saved 4 early chances in a tight deciding set before Medvedev broke to fifteen to secure the win.
Suitably, he earned the title with a point at the front of the court, with the Frenchman failing to control a shot after two hours and 38 minutes.